Solubility of gemcitabine hydrochloride
WebFeb 25, 2024 · The solution was then diluted 10× with a premade PBS solution of gemcitabine (hydrochloride salt) (12.65 mg/mL). Final concentrations of drugs were 10/1 mg/mL GT. CrEL drug suspensions were used within the same day of preparation due to instability. ... Whether a water soluble gemcitabine (Log P=−1.5) and insoluble paclitaxel ... WebGemcitabine, HCl - CAS 122111-03-9 - Calbiochem. View Price and Availability. Supelco. PHR2582. Gemcitabine hydrochloride. Pharmaceutical Secondary Standard; Certified …
Solubility of gemcitabine hydrochloride
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WebBiological Activity for Gemcitabine hydrochloride. Gemcitabine hydrochloride is a deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine … WebGemcitabine prepared as intravenous admixtures of 0.1 and 10 mg/mL as the hydrochloride salt in 5% dextrose injection and 0.9% sodium chloride injection in PVC bags and as a …
WebTest conditions included (1) reconstituted gemcitabine at a concentration of 38 mg/mL as the hydrochloride salt in 0.9% sodium chloride or sterile water for injection in the original … WebGemcitabine Hydrochloride, CAS: 122111-03-9, is a deoxycytidine analog that inhibits ribonucleotide reductase & induces apoptosis. ... Gemcitabine Hydrochloride, sc-204763, …
WebJun 1, 2024 · Gemcitabine hydrochloride is soluble in water, slightly soluble in methanol, and practically insoluble in ethanol and polar organic solvents. Gemcitabine for Injection, USP is a sterile white to off-white lyophilized powder and available as 200 mg and 1 g single-dose vials for intravenous use only. WebDec 2, 2013 · The release behavior of another anti-cancer drug gemcitabine from the PU matrix is quite different from that of PTX due to the extreme difference in water solubility between gemcitabine and PTX.PTX is practically insoluble in water, whereas gemcitabine is readily soluble in water and has a solubility of 1.55% [37,67].
WebGemcitabine is a chemotherapeutic agent used as monotherapy or in combination with other anticancer agents. In combination with [carboplatin], it is indicated for the treatment …
WebNov 25, 2024 · The empirical formula for gemcitabine HCl is C 9 H 11 F 2 N 3 O 4 • HCl. It has a molecular weight of 299.66. Gemcitabine HCl is soluble in water, slightly soluble in … simson vectorWebGemcitabine HCl (Gemzar) ... *<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and … rcs in work supportWebApr 1, 1999 · Reconstituted gemcitabine as the hydrochloride salt in the original vials is chemically stable at room temperature for 35 days but may develop crystals when stored … simson wallpaper pcWebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); >= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used … rcs invited review handbookWebGeneral description. A bioavailable, moderately toxic, deoxyctytidine analog with anti-metabolite and anti-tumor properties. Shown to be effective against a variety of tumors … rcs in textWebUse in Cancer. Gemcitabine hydrochloride is approved to be used alone or with other drugs to treat: Breast cancer that cannot be treated with or that did not respond to … simson worms ebayrcsiti