WebApr 17, 2024 · Late-onset hearing loss is known to occur long after cessation of cisplatin treatment, and these study results suggest that this delayed hearing loss may be related to long-retained cisplatin in the cochlea. Until researchers make significant progress in preventing cisplatin ototoxicity in cancer therapy, it is crucial to continue identifying ... WebJul 13, 2024 · “Around 60% to 80% of kids who get cisplatin have significant hearing loss,” Dr. Neuwelt explained. The impact of that hearing loss can be profound, he continued, including greatly increasing the risk …
Oral Administration of Caffeine Exacerbates Cisplatin-Induced Hearing Loss
WebOct 11, 2024 · An additional phenomenon that exacerbates preexisting hearing loss has been identified in patients treated with cisplatin. Those with existing hearing loss at higher frequencies prior to treatment are more likely to experience hearing loss at lower … close drawer menu open drawer menu home. the asha leader; journals. … close drawer menu open drawer menu home. the asha leader; journals. … WebOct 27, 2024 · Cisplatin entry into cochlear hair cells is mediated by various transporters, inhibitors of which have been shown to be effective for treating … flooded carpet sutherland shire
Mechanisms of Cisplatin-Induced Ototoxicity and …
WebJan 13, 2024 · Cisplatin remains a highly common chemotherapeutic for a number of cancers in both adult and pediatric populations. It is estimated that approximately 50% of chemotherapy regiments include cisplatin [26, 30].The ototoxicity created by cisplatin has a number of concerning consequences including hearing loss, tinnitus, and … WebJan 26, 2024 · Results from a new study may explain why many patients treated with the chemotherapy drug cisplatin develop lasting hearing loss. Researchers found that, in both mice and humans, cisplatin can be … WebJun 21, 2024 · In this trial, the addition of delayed sodium thiosulfate to cisplatin led to a 48% lower risk of hearing loss. Hearing loss of grade 1 or higher occurred in 63% of the children who did... flooded carpet floor mold